Factor V Leiden mutation in a case with ischemic stroke: which relationship? A case report

Angiology. 1998 Jan;49(1):79-82. doi: 10.1177/000331979804900111.

Abstract

A 50-year-old man presented spontaneous internal carotid artery dissection with ischemic stroke. He had a history of deep venous thrombosis, and an activated protein C resistance due to factor V Leiden mutation was documented. He showed no other vascular risk factor. This unusual case puts the question whether this coagulation defect may be related to the stroke occurrence.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anticoagulants / therapeutic use
  • Aortic Dissection / etiology
  • Brain Ischemia / etiology*
  • Carotid Artery, Internal
  • Carotid Stenosis / etiology
  • Cerebrovascular Disorders / etiology
  • Factor V / genetics*
  • Follow-Up Studies
  • Heparin / therapeutic use
  • Humans
  • Male
  • Middle Aged
  • Point Mutation / genetics*
  • Protein C
  • Thrombophlebitis / drug therapy
  • Thrombophlebitis / etiology
  • Warfarin / therapeutic use

Substances

  • Anticoagulants
  • Protein C
  • factor V Leiden
  • Warfarin
  • Factor V
  • Heparin