Bacteriology of inflamed and uninflamed epidermal inclusion cysts

Arch Dermatol. 1998 Jan;134(1):49-51. doi: 10.1001/archderm.134.1.49.

Abstract

Objective: To determine whether inflamed and uninflamed epidermoid cysts differ in the number and/or type of bacteria inhabiting them.

Design: A controlled study. We obtained aerobic and anaerobic bacterial culture specimens from 25 inflamed and 25 uninflamed epidermoid cysts.

Setting: A university medical center.

Patients: Nonimmunocompromised adults without recent systemic use of antibiotics.

Results: The 2 groups did not differ significantly with respect to number of bacterial isolates, "no growth" cultures, and aerobic, anaerobic, or potential pathogens cultured.

Conclusions: The microbiological milieu of inflamed epidermoid cysts is similar to that of uninflamed cysts. Possible mechanisms for inflammation are discussed.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Bacteria, Aerobic / growth & development
  • Bacteria, Aerobic / isolation & purification*
  • Bacteria, Anaerobic / growth & development
  • Bacteria, Anaerobic / isolation & purification*
  • Colony Count, Microbial
  • Cysts / microbiology*
  • Cysts / pathology
  • Erythema / pathology
  • Female
  • Gram-Positive Bacterial Infections
  • Humans
  • Inflammation
  • Keratins
  • Male
  • Middle Aged
  • Peptostreptococcus / growth & development
  • Peptostreptococcus / isolation & purification
  • Skin Diseases / microbiology*
  • Skin Diseases / pathology
  • Staphylococcal Infections
  • Staphylococcus aureus / growth & development
  • Staphylococcus aureus / isolation & purification
  • Suppuration

Substances

  • Keratins