Abstract
This pilot study compared haloperidol, fluoxetine, and placebo for reduction of agitation in 15 outpatients with AD. The two drugs were no more effective than placebo at reducing agitation in these subjects; however, both drugs produced more toxicity than did placebo.
Publication types
-
Clinical Trial
-
Comparative Study
-
Randomized Controlled Trial
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Aged
-
Alzheimer Disease / complications*
-
Antidepressive Agents, Second-Generation / adverse effects
-
Antidepressive Agents, Second-Generation / therapeutic use*
-
Antipsychotic Agents / adverse effects
-
Antipsychotic Agents / therapeutic use*
-
Double-Blind Method
-
Female
-
Fluoxetine / adverse effects
-
Fluoxetine / therapeutic use*
-
Haloperidol / adverse effects
-
Haloperidol / therapeutic use*
-
Humans
-
Male
-
Pilot Projects
-
Psychomotor Agitation / drug therapy*
-
Psychomotor Agitation / etiology*
Substances
-
Antidepressive Agents, Second-Generation
-
Antipsychotic Agents
-
Fluoxetine
-
Haloperidol