Systemic absorption of gentamicin ear drops

K M Green; D W Lappin; J W Curley; J P de Carpentier

doi:10.1017/s0022215100139076

Systemic absorption of gentamicin ear drops

J Laryngol Otol. 1997 Oct;111(10):960-2. doi: 10.1017/s0022215100139076.

Authors

K M Green¹, D W Lappin, J W Curley, J P de Carpentier

Affiliation

¹ Department of Otolaryngology, Royal Preston Hospital, UK.

PMID: 9425487
DOI: 10.1017/s0022215100139076

Abstract

Aminoglycoside-containing topical preparations are commonly used in the treatment of chronic suppurative otitis media and otitis externa. We report a case where systemic absorption of topical Gentisone HC occurred producing a serum gentamicin level of 6.2 micrograms/ml.

Publication types

Case Reports

MeSH terms

Absorption
Administration, Topical
Anti-Bacterial Agents / blood
Anti-Bacterial Agents / pharmacokinetics*
Anti-Bacterial Agents / therapeutic use
Gentamicins / blood
Gentamicins / pharmacokinetics*
Gentamicins / therapeutic use
Humans
Kidney Failure, Chronic / blood
Male
Middle Aged
Otitis Media, Suppurative / blood*
Otitis Media, Suppurative / drug therapy

Substances

Anti-Bacterial Agents
Gentamicins