Abstract
Congenital toxoplasmosis is a preventable and treatable disease with predominant neurological and ophthalmologic manifestations. These manifestations and approaches to diagnosis, treatment, and prevention of this infection are considered. Outcomes with and without treatment are emphasized. The following also are discussed: recent advances in understanding the organism; its life cycle, epidemiology, pathogenesis, and pathology; and areas in which improvements in diagnosis, treatment, and prevention are needed.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Brain Diseases / diagnosis
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Brain Diseases / etiology
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Brain Diseases / parasitology
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Brain Diseases / therapy
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Female
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Humans
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Infant, Newborn
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Pregnancy
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Pregnancy Complications, Parasitic
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Toxoplasma / physiology
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Toxoplasmosis, Congenital* / classification
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Toxoplasmosis, Congenital* / diagnosis
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Toxoplasmosis, Congenital* / etiology
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Toxoplasmosis, Congenital* / parasitology
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Toxoplasmosis, Congenital* / therapy