Clinical implications and possible association of malposition of the branch pulmonary arteries with DiGeorge syndrome and microdeletion of chromosomal region 22q11

Am J Cardiol. 1997 Dec 15;80(12):1624-7. doi: 10.1016/s0002-9149(97)00782-0.

Abstract

We describe a series of 10 patients with malposition of the branch pulmonary arteries (4 patients with crossing [crossed pulmonary arteries] and 6 patients without crossing), 2 of whom had a short main pulmonary artery segment that resulted in iatrogenic right pulmonary artery stenosis after pulmonary artery band placement. DiGeorge syndrome was seen in 5 patients and 4 had microscopic deletion of chromosomal region 22q11.

MeSH terms

  • Adolescent
  • Chromosome Deletion*
  • Chromosomes, Human, Pair 22*
  • DiGeorge Syndrome / complications*
  • DiGeorge Syndrome / genetics
  • Female
  • Heart Defects, Congenital / complications
  • Heart Defects, Congenital / genetics
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Pulmonary Artery / abnormalities*