A study was conducted during 5 years to determine the epidemiological clinical profile and the evolution of legs erysipelas in patients attending Lome teaching hospital. During this period, 60 subjects (43 females et 17 males) were hospitalized for legs erysipelas. The average age was 40 years old. General facilitating factors were noted in 58% of the patients (n = 35), and local in 50% of cases (n = 30). The first line treatment was in all patients penicillin G. Satisfactory results were observed in 70%. Local complications were noted in 10% (n = 6), and recurrence in 17% (n = 10). The erysipela is common in hospital environment. The precocious penicillinotherapy allowed to have satisfactory results.