Purpose: To report the singular case of a patient who developed three noncontiguous uveal melanomas over a 30-year period.
Method: Case report.
Result: Systemic evaluation of a 50-year-old man with an iris melanoma and bilateral choroidal melanomas disclosed no evidence of metastases or other primary neoplastic disease.
Conclusion: Although rare, the possibility of bilateral and multifocal uveal melanoma should be recognized.