Lymphocytes with cerebriform nuclei in chronic B-cell lymphoproliferative diseases

Leuk Res. 1997 Sep;21(9):893-5. doi: 10.1016/s0145-2126(97)00034-9.

Abstract

Two patients with chronic lymphoproliferative diseases, a splenic marginal zone lymphoma and hairy cell leukaemia variant, were reported. In both diseases a B-immunophenotype was demonstrated but a variable percentage of lymphoid cells (30 and 52%) showed a highly irregular nuclear outline, sometimes mimicking the nuclei of Sézary cells.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • B-Lymphocytes / pathology*
  • Biomarkers, Tumor / analysis
  • Cell Nucleus / ultrastructure*
  • Diagnosis, Differential
  • Female
  • Humans
  • Leukemia, Hairy Cell / pathology
  • Leukemia, Hairy Cell / surgery
  • Lymphoproliferative Disorders / diagnosis
  • Lymphoproliferative Disorders / pathology*
  • Lymphoproliferative Disorders / surgery
  • Middle Aged
  • Sezary Syndrome / diagnosis
  • Sezary Syndrome / pathology*
  • Splenectomy

Substances

  • Biomarkers, Tumor