Radiation-associated synovial sarcoma

Hum Pathol. 1997 Nov;28(11):1325-8. doi: 10.1016/s0046-8177(97)90213-6.

Abstract

We describe a case of synovial sarcoma occurring in a 36 year-old woman, 8 years after radiation therapy for Hodgkin's disease. The tumor showed histological, immunohistochemical, ultrastructural, and molecular features diagnostic of synovial sarcoma. To our knowledge, this is the first report of a fully documented case of radiation associated synovial sarcoma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biomarkers, Tumor / analysis
  • Female
  • Hodgkin Disease / radiotherapy
  • Humans
  • Immunohistochemistry
  • Keratins / analysis
  • Microscopy, Electron
  • Mucin-1 / analysis
  • Neoplasms, Radiation-Induced / chemistry
  • Neoplasms, Radiation-Induced / etiology*
  • Neoplasms, Radiation-Induced / genetics
  • Neoplasms, Radiation-Induced / pathology
  • Neoplasms, Radiation-Induced / ultrastructure
  • Peripheral Nervous System Neoplasms / chemistry
  • Peripheral Nervous System Neoplasms / etiology*
  • Peripheral Nervous System Neoplasms / genetics
  • Peripheral Nervous System Neoplasms / pathology
  • Peripheral Nervous System Neoplasms / ultrastructure
  • Sarcoma, Synovial / chemistry
  • Sarcoma, Synovial / etiology*
  • Sarcoma, Synovial / genetics
  • Sarcoma, Synovial / pathology
  • Sarcoma, Synovial / ultrastructure
  • Translocation, Genetic

Substances

  • Biomarkers, Tumor
  • Mucin-1
  • Keratins