A new applicator design for endocavitary brachytherapy of cancer in the nasopharynx

Radiother Oncol. 1997 Oct;45(1):95-8. doi: 10.1016/s0167-8140(97)00105-9.

Abstract

Introduction: In attempting to improve local tumor control by higher doses of radiation, there has been a resurgence of interest in the implementation of brachytherapy in the management of primary and recurrent cancers of the nasopharynx. Brachytherapy with its steep dose fall-off is of particular interest because of the proximity of critical dose limiting structures. Recent developments in brachytherapy, such as the introduction of pulsed-dose-rate and high-dose-rate computerized afterloaders, have encouraged further evolution of brachytherapy techniques.

Materials and methods: We have designed an inexpensive, re-usable and flexible silicone applicator, tailored to the shape of the soft tissues of the nasopharynx, which can be used with either low-dose-rate brachytherapy or high (pulsed)-dose-rate remote controlled afterloaders.

Results and conclusions: This Rotterdam nasopharynx applicator proved to be easy to introduce, patient friendly and can remain in situ for the duration of the treatment (2-6 days). The design, technique of application and the first consecutive 5 years of clinical experience in using this applicator are presented.

Publication types

  • Clinical Trial

MeSH terms

  • Brachytherapy / instrumentation*
  • Brachytherapy / methods
  • Carcinoma, Squamous Cell / radiotherapy*
  • Dose-Response Relationship, Radiation
  • Equipment Design
  • Equipment Safety
  • Humans
  • Nasopharyngeal Neoplasms / radiotherapy*
  • Radiotherapy Dosage
  • Treatment Outcome