Double-blind trial of flumazenil in hemiballismus

Clin Neuropharmacol. 1994 Oct;17(5):470-2. doi: 10.1097/00002826-199410000-00010.

Abstract

Three patients with hemiballismus received intravenous flumazenil and placebo in a double-blind cross-over study aimed to investigate whether an antagonistic action at the level of the GABA-benzodiazepine receptors may improve choreoballistic movements. No clinical benefit was seen.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cross-Over Studies
  • Double-Blind Method
  • Female
  • Flumazenil / therapeutic use*
  • GABA Antagonists / therapeutic use*
  • Humans
  • Movement Disorders / drug therapy*
  • Placebos

Substances

  • GABA Antagonists
  • Placebos
  • Flumazenil