A phase I study of adenovirus mediated gene transfer of interleukin 2 cDNA into metastatic breast cancer or melanoma

Hum Gene Ther. 1997 Jul 20;8(11):1403-14. doi: 10.1089/hum.1997.8.11-1403.
No abstract available

Publication types

  • Clinical Trial
  • Clinical Trial, Phase I
  • Clinical Trial, Phase II
  • Multicenter Study

MeSH terms

  • Adenoviridae / genetics*
  • Adenoviridae / physiology
  • Adenoviridae Infections / etiology
  • Adenoviridae Infections / transmission
  • Animals
  • Breast Neoplasms / therapy*
  • Clinical Protocols*
  • Disease Models, Animal
  • Female
  • Gene Transfer Techniques*
  • Genetic Therapy / methods*
  • Genetic Therapy / standards
  • Genetic Vectors
  • Humans
  • Interleukin-2 / adverse effects
  • Interleukin-2 / genetics
  • Interleukin-2 / therapeutic use*
  • Melanoma / therapy*
  • Mice
  • Mice, Transgenic
  • Pilot Projects
  • Risk Factors
  • Virus Replication

Substances

  • Interleukin-2