Conservation of the Escherichia coli dnaX programmed ribosomal frameshift signal in Salmonella typhimurium

J Bacteriol. 1997 Jul;179(13):4438-42. doi: 10.1128/jb.179.13.4438-4442.1997.

Abstract

Escherichia coli DNA polymerase III subunits tau and gamma are produced from one gene, dnaX, by a programmed ribosomal frameshift which generates the C terminal of gamma within the tau reading frame. To help evaluate the role of the dispensable gamma, the distribution of tau and gamma homologs in several other species and the sequence of the Salmonella typhimurium dnaX were determined. All four enterobacteria tested produce tau and gamma homologs. S. typhimurium dnaX is 83% identical to E. coli dnaX, but all four components of the frameshift signal are 100% conserved.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Bacterial Proteins / genetics*
  • Base Sequence
  • Conserved Sequence*
  • DNA Polymerase III / genetics*
  • DNA, Bacterial
  • Escherichia coli / enzymology*
  • Escherichia coli / genetics
  • Molecular Sequence Data
  • Nucleic Acid Conformation
  • Ribosomes
  • Salmonella typhimurium / enzymology*
  • Salmonella typhimurium / genetics
  • Sequence Homology, Amino Acid

Substances

  • Bacterial Proteins
  • DNA, Bacterial
  • DnaX protein, Bacteria
  • DNA Polymerase III

Associated data

  • GENBANK/U66040