Intravenous organophosphate injection: an unusual way of intoxication

Hum Exp Toxicol. 1997 May;16(5):279-80. doi: 10.1177/096032719701600509.

Abstract

Organophosphate insecticides strongly inhibit both true cholinesterase and pseudocholinesterase activities. In this report, we have reported a patient who injected himself a strong organophosphate compound, methamidophos, and showed the typical clinical picture of organophosphate intoxication. As far as we know, this is the first case of intoxication by intravenous (i.v.) injection. With the appropriate therapy, his symptoms disappeared in a few days.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antidotes / therapeutic use
  • Atropine / therapeutic use
  • Cholinesterase Inhibitors / administration & dosage
  • Cholinesterase Inhibitors / poisoning*
  • Cholinesterase Reactivators / therapeutic use
  • Humans
  • Injections, Intravenous
  • Insecticides / administration & dosage
  • Insecticides / poisoning*
  • Male
  • Muscarinic Antagonists / therapeutic use
  • Nervous System Diseases / chemically induced
  • Nervous System Diseases / drug therapy
  • Organothiophosphorus Compounds / poisoning*
  • Pralidoxime Compounds / therapeutic use
  • Schizophrenia / complications
  • Suicide, Attempted*

Substances

  • Antidotes
  • Cholinesterase Inhibitors
  • Cholinesterase Reactivators
  • Insecticides
  • Muscarinic Antagonists
  • Organothiophosphorus Compounds
  • Pralidoxime Compounds
  • Atropine
  • methamidophos
  • pralidoxime