Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials

Cancer Treat Rev. 1997 Jan;23(1):35-61. doi: 10.1016/s0305-7372(97)90019-0.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Animals
  • Antineoplastic Agents, Alkylating* / chemistry
  • Antineoplastic Agents, Alkylating* / pharmacology
  • Clinical Trials, Phase I as Topic
  • Clinical Trials, Phase II as Topic
  • Dacarbazine / analogs & derivatives*
  • Dacarbazine / chemistry
  • Dacarbazine / pharmacology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasms, Experimental / drug therapy
  • Temozolomide
  • Tumor Cells, Cultured / drug effects

Substances

  • Antineoplastic Agents, Alkylating
  • Dacarbazine
  • Temozolomide