Purpose: Cases of angle-closure glaucoma in patients with familial exudative vitreoretinopathy have been reported secondary to neovascularization of the anterior segment. Cases secondary to nonneovascular mechanisms have not been previously reported.
Methods: Two cases are presented of angle-closure glaucoma as a result of a nonneovascular mechanism.
Results: Neovascularization was found to be a very unlikely explanation for the angle closure in these two cases.
Conclusion: There may be an association between familial exudative vitreoretinopathy and angle-closure glaucoma as a direct result of a retrolental process or more likely a relative lens-iris pupillary block with a large lens.