The spectrum of chronic mature T-cell disorders: a report of four cases

Neth J Med. 1996 Apr;48(4):133-9.

Abstract

We describe four patients with a mature T-cell disorder. These four specific entities belong to a group formerly called "T-cell chronic lymphocytic leukaemia" (T-CLL). Nowadays we understand that these chronic T-cell lymphoproliferative disorders consist of four different entities. They stand out as well-described and separate disorders on the basis of their clinical, immunophenotypic and cytogenetic properties. Unfortunately, the majority of patients have a bad response to chemotherapy. The purine analogs may offer a better prognosis for some patients.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aged, 80 and over
  • Diagnosis, Differential
  • Humans
  • Leukemia, T-Cell* / complications
  • Leukemia, T-Cell* / diagnosis
  • Leukemia, T-Cell* / drug therapy
  • Lymphoproliferative Disorders* / complications
  • Lymphoproliferative Disorders* / diagnosis
  • Lymphoproliferative Disorders* / drug therapy
  • Male
  • Mycosis Fungoides* / complications
  • Mycosis Fungoides* / diagnosis
  • Mycosis Fungoides* / drug therapy
  • Prognosis
  • Purines / therapeutic use
  • Sezary Syndrome

Substances

  • Purines