Mapping of the genetically independent chicken major histocompatibility complexes B@ and RFP-Y@ to the same microchromosome by two-color fluorescent in situ hybridization

V Fillon; R Zoorob; M Yerle; C Auffray; A Vignal

doi:10.1159/000134445

Mapping of the genetically independent chicken major histocompatibility complexes B@ and RFP-Y@ to the same microchromosome by two-color fluorescent in situ hybridization

Cytogenet Cell Genet. 1996;75(1):7-9. doi: 10.1159/000134445.

Authors

V Fillon¹, R Zoorob, M Yerle, C Auffray, A Vignal

Affiliation

¹ Laboratoire de Génétique Cellulaire, Centre INRA de Toulouse-Auzeville, Castanet Tolosan, France.

PMID: 8995478
DOI: 10.1159/000134445

Abstract

The chicken MHC is organized in two genetically independent gene complexes B@ and RFP-Y@. Previous studies have shown the localization of the B@ complex on a small microchromosome. By using two-color fluorescent in situ hybridization, we demonstrate the localization of the RFP-Y@ complex to the same chromosome. A recombination hot spot between the two loci might account for their independent segregation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Chickens / genetics*
Chromosome Mapping*
Cosmids
In Situ Hybridization, Fluorescence
Major Histocompatibility Complex / genetics*
Multigene Family*
Recombination, Genetic