Comparison of clinical symptoms in autism and Asperger's disorder

J Am Acad Child Adolesc Psychiatry. 1996 Nov;35(11):1523-31. doi: 10.1097/00004583-199611000-00022.

Abstract

Objective: To determine what clinical symptoms clinicians have been using to distinguish between Asperger's disorder (AsD) and autistic disorder (AD).

Method: Parents of children and adolescents with high-functioning AD (n = 48) and AsD (n = 69) were given a structured interview based on DSM-III-R and ICD-10 diagnostic criteria. Information regarding early and current symptom presentation and family, developmental, and verbal mental age information were collected. Logistic regression analyses were conducted to determine which variables best predicted clinician's diagnosis.

Results: A number of clinical variables predicted diagnosis. Delayed language onset was the only variable of the family and developmental variables that predicted diagnosis. The AsD group was also significantly higher than the AD group in verbal mental age.

Conclusion: Clinicians appear to be diagnosing AsD and AD on the basis of published research and case study accounts. The findings question whether DSM-IV and ICD-10 criteria adequately describe the AsD individual, particularly in the communication domain.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Autistic Disorder / classification
  • Autistic Disorder / diagnosis*
  • Autistic Disorder / genetics
  • Autistic Disorder / psychology
  • Child
  • Diagnosis, Differential
  • Female
  • Humans
  • Male
  • Personality Assessment
  • Psychiatric Status Rating Scales
  • Risk Factors
  • Syndrome