Rapid and sensitive method for the detection of Mycobacterium chlorophenolicum PCP-1 in soil based on 16S rRNA gene-targeted PCR

Appl Environ Microbiol. 1996 Apr;62(4):1478-80. doi: 10.1128/aem.62.4.1478-1480.1996.

Abstract

A method based on 16S rRNA gene-targeted PCR and oligonucleotide probing was developed for detecting Mycobacterium chlorophenolicum PCP-1 in soil. The primers and probe were specific for PCP-1 in DNA extracts of three soils. The method allowed for PCP-1 detection in soil with a detection limit of 3 x 10(2) cells per g.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • DNA Primers / genetics
  • DNA, Bacterial / genetics
  • DNA, Ribosomal / genetics
  • Evaluation Studies as Topic
  • Gene Targeting
  • Genes, Bacterial
  • Molecular Sequence Data
  • Mycobacterium / classification
  • Mycobacterium / genetics*
  • Mycobacterium / isolation & purification*
  • Polymerase Chain Reaction / methods*
  • Polymerase Chain Reaction / statistics & numerical data
  • RNA, Bacterial / genetics*
  • RNA, Ribosomal, 16S / genetics*
  • Sensitivity and Specificity
  • Sequence Homology, Nucleic Acid
  • Soil Microbiology*
  • Species Specificity

Substances

  • DNA Primers
  • DNA, Bacterial
  • DNA, Ribosomal
  • RNA, Bacterial
  • RNA, Ribosomal, 16S