Intrathecal Rubella and RNA antibody synthesis in multiple sclerosis and progressive rubella panencephalitis

Biomedicine. 1977 Jun;27(4):139-41.

Abstract

The assay of serum and CSF rubella and RNA antibodies in 3 patients (2 multiple sclerosis and 1 progressive rubella panencephalitis) shows their predominant local (intrathecal) syntheses. This correlation suggests that RNA antibodies may be directed against the viral genome itself.

MeSH terms

  • Adolescent
  • Adult
  • Antibodies / analysis
  • Antibodies / cerebrospinal fluid*
  • Antibodies, Viral / analysis
  • Antibodies, Viral / cerebrospinal fluid
  • DNA / immunology
  • Encephalitis / immunology*
  • Humans
  • Immunoglobulin G / cerebrospinal fluid
  • Male
  • Multiple Sclerosis / immunology*
  • RNA / immunology*
  • Rubella / immunology*
  • Rubella virus / immunology*

Substances

  • Antibodies
  • Antibodies, Viral
  • Immunoglobulin G
  • RNA
  • DNA