Delayed onset of angioedema with angiotensin-converting enzyme inhibitors: case report and review of the literature

Pharmacotherapy. 1996 Jul-Aug;16(4):675-9.

Abstract

The angiotensin-converting enzyme inhibitors have gained widespread application in the management of hypertension and congestive heart failure, and after myocardial infarction. They are generally considered safe drugs, but there are a number of reports of angioedema associated with their use. In general, angioedema occurs within hours to days after initiation of therapy, and only a limited number of reports document a delayed onset. Our patient experienced angioedema after 14 months of therapy with benazepril.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Angioedema / chemically induced*
  • Angioedema / physiopathology
  • Angiotensin-Converting Enzyme Inhibitors / adverse effects*
  • Benzazepines / adverse effects*
  • Female
  • Humans
  • Tongue Diseases / chemically induced*
  • Tongue Diseases / physiopathology

Substances

  • Angiotensin-Converting Enzyme Inhibitors
  • Benzazepines
  • benazepril