Background: Vitreous cysts are rare, and their origin and morphologic features unclear. The authors present ultrastructural observations made in a case of a 47-year-old woman who, after undergoing retinal detachment surgery on several occasions, developed disturbing vitreous opacities and a solitary cystic structure in the anterior vitreous cavity.
Methods: Clinical and intraoperative biomicroscopy and histologic examination by light microscopy and transmission electron microscopy were performed.
Results: The cystic structure was attached at its posterior aspect to a vitreous membrane and enclosed within a vitreous body lacuna. It had an oval form with a smooth surface and was translucent. Histology showed the cyst wall to consist of retinal tissue with gliotic changes that had placed itself within the vitreous.
Conclusion: The morphologic studies do not rule out the possibility of a congenital cyst. However, the authors presume that in association with the retinal detachment or the operations, a displacement of retinal tissue into the vitreous body occurred from which the cyst developed.