Detection of a point mutation in poliovaccines with a water soluble carbodiimide reaction of DNA heteroduplexes

MeSH terms

• Animal Testing Alternatives / methods
• Animals
• Carbodiimides
• DNA, Viral / genetics
• Nucleic Acid Heteroduplexes
• Point Mutation*
• Poliovirus Vaccine, Inactivated / genetics*
• Polymerase Chain Reaction
• Solubility
• Water