Abstract
We describe a case of neurologic manifestations including coma, convulsion and eye movement disorders, associated with hypomagnesemia and hypocalcemia in a patient treated with cisplatin for an ovarian adenocarcinoma. Pathophysiological mechanisms involve renal tubular damage leading to renal magnesium wasting and related hypocalcemia.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adenocarcinoma / drug therapy
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Antineoplastic Agents / adverse effects*
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Carboplatin / adverse effects*
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Cisplatin / adverse effects*
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Coma / chemically induced
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Female
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Humans
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Hypocalcemia / chemically induced*
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Magnesium / blood*
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Middle Aged
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Ocular Motility Disorders / chemically induced
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Ovarian Neoplasms / drug therapy
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Seizures / chemically induced
Substances
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Antineoplastic Agents
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Carboplatin
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Magnesium
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Cisplatin