Intravenous infusion of prostacyclin to prevent platelet thrombus during microvascular anastomoses

Br J Plast Surg. 1996 Jun;49(4):249-50. doi: 10.1016/s0007-1226(96)90061-2.

Abstract

Two cases are presented where the use of epoprostenol sodium (prostacyclin) was used intraoperatively to prevent platelet thrombus during arterial microvascular anastomoses. Both patients required a free muscle transfer at an unfavourable time following injury when platelet thrombus formation was a significant risk.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anastomosis, Surgical
  • Blood Platelets / physiology
  • Epoprostenol / therapeutic use*
  • Humans
  • Male
  • Microcirculation / surgery
  • Microsurgery
  • Muscles / blood supply
  • Platelet Aggregation Inhibitors / therapeutic use*
  • Postoperative Complications / prevention & control*
  • Surgical Flaps*
  • Thrombolytic Therapy*
  • Thrombosis / prevention & control*

Substances

  • Platelet Aggregation Inhibitors
  • Epoprostenol