The authors measured the velocity of the ophthalmic arterial blood flow with color Doppler sonography (Acuson-128, USA) in 246 eyes of 123 normal persons to evaluate exactly the changes of the blood supply in all ischemic fundus diseases and provide the reliable reference basis for the clinic. The average velocity of the ophthalmic arterial flow of the normal in the maximum contraction period (peak systolic velocity, PSV) is respectively 36.44 +/- 8.35cm/sec on the right and 36.94 +/- 11.30cm/sec on the left. There were no significant differences in PSV between the right and left eyes and between the male and female persons. We found that PSV of the ophthalmic artery in persons over 41 years old was significantly different from that in persons below that age, suggesting the age of 41 years old be the beginning of the senile process of systemic small blood vessels and providing a reference for anti-sensility. In the mean time, the velocity of ophthalmic arterial blood flow was also evaluated in 18 eyes with the acute attack of acute angle-closure glaucoma and 15 eyes at pre-clinical stage.