We report a case where a patient developed recurrence of an adenocarcinoma of the stomach ten years after primary surgery. Besides the late recurrence, the case is interesting as the patient participated in a trial investigating the effect of cimetidine on survival after gastric cancer and received cimetidine for two years after surgery. Considering the well documented anti-tumour and immunomodulating effects of histamine type-2 receptor antagonists, it might be interesting to examine the effect on survival after surgery for gastric cancer in patients receiving prolonged treatment with such an antagonist.