Technetium-99m polyphosphate bone scans of three elderly patients with osteolytic Paget's disease are presented. Similar findings of increased accumulation of the tracer in the region of diseased bone, and even greater uptake at the advancing edge of osteolysis, are seen in both the skull and long bones. The reason for this scintigraphic pattern is postulated from histologic findings of osteolytic Paget's disease.