Standardization of coronary vasomotor tone with intracoronary nitroglycerin

Am J Cardiol. 1996 Jul 1;78(1):120-3. doi: 10.1016/s0002-9149(96)00243-3.

Abstract

Maximal, reproducible, and thus "standardized" dilation of epicardial coronary arteries can be easily achieved with intracoronary bolus administration of 0.1 mg nitroglycerin without considerable decrease in blood pressure. The addition of other nitrocompounds or calcium antagonists cannot increase coronary dilation after nitroglycerin, but may be hampered by adverse effects.

Publication types

  • Comparative Study

MeSH terms

  • Blood Pressure / drug effects
  • Calcium Channel Blockers / administration & dosage
  • Calcium Channel Blockers / pharmacology
  • Case-Control Studies
  • Coronary Angiography*
  • Coronary Disease / diagnostic imaging
  • Coronary Disease / physiopathology
  • Coronary Vessels / drug effects*
  • Coronary Vessels / physiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Molsidomine / administration & dosage
  • Molsidomine / analogs & derivatives
  • Molsidomine / pharmacology
  • Nisoldipine / administration & dosage
  • Nisoldipine / pharmacology
  • Nitroglycerin / administration & dosage
  • Nitroglycerin / pharmacology*
  • Reproducibility of Results
  • Time Factors
  • Vasodilation / drug effects*
  • Vasodilator Agents / administration & dosage
  • Vasodilator Agents / pharmacology*

Substances

  • Calcium Channel Blockers
  • Vasodilator Agents
  • Nisoldipine
  • linsidomine
  • Molsidomine
  • Nitroglycerin