Cloning and chromosomal localization of a novel gene-encoding a human beta 2-integrin alpha subunit

Gene. 1996 Jun 1;171(2):291-4. doi: 10.1016/0378-1119(95)00869-1.

Abstract

We isolated a partial genomic clone encoding ITGAD, a novel beta 2-integrin alpha subunit. The ITGAD gene is highly homologous to the three previously known alpha subunit-encoding genes, that compose the beta 2 integrin family, in deduced amino acid sequence, intron/exon structure and mapping location (chromosome 16p11).

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • CD11 Antigens
  • Chromosome Mapping
  • Chromosomes, Human, Pair 16*
  • Cloning, Molecular
  • Humans
  • Integrin alpha Chains
  • Integrins / genetics*
  • Molecular Sequence Data
  • Receptors, Cytoadhesin*
  • Sequence Analysis, DNA
  • Sequence Homology, Amino Acid

Substances

  • CD11 Antigens
  • ITGAD protein, human
  • Integrin alpha Chains
  • Integrins
  • Receptors, Cytoadhesin

Associated data

  • GENBANK/U40274
  • GENBANK/U40275
  • GENBANK/U40276
  • GENBANK/U40277
  • GENBANK/U40278
  • GENBANK/U40279
  • SWISSPROT/P11215
  • SWISSPROT/P20701
  • SWISSPROT/P20702