Evidence for a model ancestral viroid

Nucleic Acids Symp Ser. 1995:(33):143-4.

Abstract

The generation of a phylogenetic tree of viroids and viroid-like plant satellite RNAs via computer analysis, coupled with several conspicuous biochemical characteristics of the rolling circle replication of these RNAs -including both self-cleavage and self-ligation- leads us to propose the peach latent mosaic viroid (PLMVd) as a current "living fossil" dating from a precellular world. Incorporated within this proposal is a revised mechanism of PLMVd rolling circle replication which requires a minimal protein involvement.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Evolution, Molecular*
  • Models, Genetic*
  • Phylogeny
  • Plants / genetics
  • Plants / virology
  • RNA / genetics
  • RNA, Circular
  • RNA, Plant / genetics
  • RNA, Satellite
  • RNA, Viral / genetics
  • Viroids / genetics*
  • Viroids / physiology
  • Virus Replication / genetics

Substances

  • RNA, Circular
  • RNA, Plant
  • RNA, Satellite
  • RNA, Viral
  • RNA