SarCNU (2-chloroethyl-3-sarcosinamide-1-nitrosourea): a novel analogue of chloroethylnitrosourea that is transported by the catecholamine uptake2 carrier, which mediates increased cytotoxicity

Cancer Chemother Pharmacol. 1996;37(6):505-8. doi: 10.1007/s002800050421.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Biological Transport
  • Carmustine / analogs & derivatives*
  • Carmustine / metabolism
  • Carrier Proteins / metabolism*
  • Catecholamine Plasma Membrane Transport Proteins
  • Catecholamines / metabolism
  • Humans
  • Membrane Transport Proteins*
  • Sarcosine / analogs & derivatives
  • Sarcosine / metabolism
  • Tumor Cells, Cultured

Substances

  • Carrier Proteins
  • Catecholamine Plasma Membrane Transport Proteins
  • Catecholamines
  • Membrane Transport Proteins
  • N-methylglycinamide
  • 2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide
  • Carmustine
  • Sarcosine