Abstract
A new sesquiterpene pyridine alkaloid, celahinine A [1], and the related known polyester celahin A, as well as the known cytotoxic sesquiterpene pyridine alkaloid emarginatine A [2], were isolated from Celastrus hindsii. The structure of 1 was determined by 2D nmr techniques and was also confirmed by spectral comparison with the related 2.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Antineoplastic Agents, Phytogenic / chemistry
-
Antineoplastic Agents, Phytogenic / isolation & purification*
-
Antineoplastic Agents, Phytogenic / pharmacology
-
Drug Screening Assays, Antitumor
-
Drugs, Chinese Herbal / chemistry
-
Drugs, Chinese Herbal / isolation & purification*
-
Drugs, Chinese Herbal / pharmacology
-
Humans
-
Magnetic Resonance Spectroscopy
-
Molecular Structure
-
Pyridines / chemistry
-
Pyridines / isolation & purification*
-
Pyridines / pharmacology
-
Sesquiterpenes / chemistry
-
Sesquiterpenes / isolation & purification*
-
Sesquiterpenes / pharmacology
-
Spectrophotometry, Infrared
-
Tumor Cells, Cultured
Substances
-
Antineoplastic Agents, Phytogenic
-
Drugs, Chinese Herbal
-
Pyridines
-
Sesquiterpenes
-
celahinine A