Abstract
Cell polarization is often accompanied by cytoskeletal rearrangements. Two signalling proteins, a GTPase and a kinase, are required for both actin and microtubule rearrangements. Are these two systems coupled?
MeSH terms
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Animals
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Cell Cycle Proteins / metabolism
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Cell Polarity / physiology*
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Cytoskeleton / metabolism
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GTP Phosphohydrolases / metabolism*
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GTP-Binding Proteins / metabolism
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Humans
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Microtubules / metabolism
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Protein Kinases / metabolism*
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Signal Transduction / physiology*
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cdc42 GTP-Binding Protein
Substances
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Cell Cycle Proteins
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Protein Kinases
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GTP Phosphohydrolases
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GTP-Binding Proteins
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cdc42 GTP-Binding Protein