Clear cell chondrosarcomas arising from rare sites

Pathol Int. 1995 Sep;45(9):684-90. doi: 10.1111/j.1440-1827.1995.tb03522.x.

Abstract

Three cases are reported of clear cell chondrosarcoma arising from unusual sites: talus, rib and vertebra. Radiographically, two tumors showed osteolytic features and the vertebral tumor showed osteoplastic change. Histologically, all tumors consisted of clear cells that had a centrally placed nucleus surrounded by clear cytoplasm, osteoclast-like giant cells, areas of conventional chondrosarcoma, and various amounts of reactive bone. The tumor in the talus was initially diagnosed as benign chondroblastoma, but it recurred. The rib tumor showed marked cystic formation stimulating aneurysmal bone cyst. The osteoplastic radiographic feature in vertebral tumor was considered to be due to the abundant bone formation.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Bone Neoplasms / diagnostic imaging
  • Bone Neoplasms / pathology*
  • Bone Neoplasms / therapy
  • Calcinosis / diagnostic imaging
  • Chondrosarcoma / diagnostic imaging
  • Chondrosarcoma / pathology*
  • Chondrosarcoma / therapy
  • Female
  • Humans
  • Immunohistochemistry
  • Male
  • Neoplasm Recurrence, Local
  • Osteolysis / diagnostic imaging
  • Ribs
  • S100 Proteins / analysis
  • Spinal Neoplasms / diagnostic imaging
  • Spinal Neoplasms / pathology*
  • Spinal Neoplasms / therapy
  • Talus
  • Thoracic Vertebrae
  • Tomography, X-Ray Computed

Substances

  • S100 Proteins