Abstract
Conventional protein kinase Cs have two conserved regulatory domains, C1 and C2, shared by many other membrane-interacting proteins. The structures of a C1 and a C2 domain provide insights into how they function.
MeSH terms
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Amino Acid Sequence
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Animals
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Binding Sites
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Calcium / metabolism
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Conserved Sequence
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Diglycerides / metabolism
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Humans
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Molecular Sequence Data
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Phorbol Esters / metabolism
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Phosphatidylserines / metabolism
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Protein Conformation
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Protein Kinase C / chemistry
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Protein Kinase C / metabolism*
Substances
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Diglycerides
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Phorbol Esters
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Phosphatidylserines
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Protein Kinase C
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Calcium