EGF: new tricks for an old growth factor

Curr Opin Cell Biol. 1993 Apr;5(2):261-4. doi: 10.1016/0955-0674(93)90113-5.

Abstract

During the past year, the biology of epidermal growth factor (EGF) has been investigated in lower organisms (Caenorhabditis elegans, Drosophila and bacteria). These experiments have produced some surprising results: the identification of defects produced by mutation of EGF-like genes; the role of EGF receptors in bacterial invasion; and the role of EGF-like precursors as receptors for a bacteria toxin.

Publication types

  • Review

MeSH terms

  • Animals
  • Caenorhabditis elegans
  • Drosophila
  • Epidermal Growth Factor / physiology*
  • ErbB Receptors / physiology*
  • Heparin-binding EGF-like Growth Factor
  • Intercellular Signaling Peptides and Proteins
  • Phosphorylation
  • Receptors, Cell Surface*
  • Receptors, Cholinergic / chemistry
  • Salmonella typhimurium

Substances

  • Heparin-binding EGF-like Growth Factor
  • Intercellular Signaling Peptides and Proteins
  • Receptors, Cell Surface
  • Receptors, Cholinergic
  • Epidermal Growth Factor
  • ErbB Receptors