(S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide [(S)-WAY-100135]: a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors

J Med Chem. 1993 May 14;36(10):1509-10. doi: 10.1021/jm00062a028.

Authors

I A Cliffe¹, C I Brightwell, A Fletcher, E A Forster, H L Mansell, Y Reilly, C Routledge, A C White

Affiliation

¹ Department of Medicinal Chemistry, Wyeth Research (UK), Taplow, Berkshire, England.

PMID: 8496920
DOI: 10.1021/jm00062a028

No abstract available

MeSH terms

Animals
Binding Sites
Piperazines / metabolism
Piperazines / pharmacology*
Rats
Receptors, Serotonin / metabolism
Serotonin Antagonists*
Stereoisomerism
Synapses / drug effects

Substances

Piperazines
Receptors, Serotonin
Serotonin Antagonists
WAY 100135