The classification of amyloid and amyloidosis has undergone several revisions. The 1990 revision of the nomenclature at the 6th Internal Symposium on Amyloidosis in Oslo has been widely accepted and the basis for nomenclature and classification is the fibril protein making up the amyloid deposits. The liver is a major site of amyloid deposition in the disseminated form of the disease. Many studies have shown that the morphologic distribution of amyloid within the liver is not a reliable method for distinguishing AA from AL amyloidosis.