Cyclic sulfolanes as novel and high affinity P2 ligands for HIV-1 protease inhibitors

J Med Chem. 1993 Apr 2;36(7):924-7. doi: 10.1021/jm00059a019.
No abstract available

MeSH terms

  • Binding Sites
  • HIV Protease Inhibitors / chemical synthesis*
  • HIV Protease Inhibitors / metabolism
  • Heterocyclic Compounds / chemical synthesis*
  • Heterocyclic Compounds / metabolism
  • Heterocyclic Compounds / pharmacology
  • Ligands
  • Structure-Activity Relationship
  • Sulfones / chemical synthesis*
  • Sulfones / metabolism
  • Sulfones / pharmacology

Substances

  • HIV Protease Inhibitors
  • Heterocyclic Compounds
  • Ligands
  • Sulfones