Interleukin-2 receptor signal transduction: translocation of active serine-threonine kinase Raf-1 from IL-2 receptor into cytosol depends on IL-2-induced tyrosine kinase activation

Transplant Proc. 1993 Feb;25(1 Pt 1):109-10.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Cells, Cultured
  • Cytosol / metabolism
  • Enzyme Activation
  • Humans
  • Interleukin-2 / pharmacology
  • Lymphocyte Activation
  • Protein Serine-Threonine Kinases / metabolism*
  • Protein-Tyrosine Kinases / metabolism*
  • Proto-Oncogene Proteins / metabolism*
  • Proto-Oncogene Proteins c-raf
  • Receptors, Interleukin-2 / drug effects
  • Receptors, Interleukin-2 / physiology*
  • Signal Transduction*
  • T-Lymphocytes / drug effects
  • T-Lymphocytes / enzymology
  • T-Lymphocytes / immunology*

Substances

  • Interleukin-2
  • Proto-Oncogene Proteins
  • Receptors, Interleukin-2
  • Protein-Tyrosine Kinases
  • Protein Serine-Threonine Kinases
  • Proto-Oncogene Proteins c-raf