Nonmental-backed, cemented, unicompartmental knee arthroplasty has a survivorship rate in this multicenter investigation at ten years of 91.4% (+/- 2.8). High levels of patient weight were associated with increased need for revision arthroplasty. Overall, men had a lower revision rate (2.4%) compared with women (3.9%). Valgus postoperative alignment was minimally associated with progression of disease as a cause for revision. No difference in revision rates between medial and lateral compartmental arthroplasty was noted. The theoretical clinical benefits of the use of metal-backed tibial components will need to be reevaluated in light of these findings.