Primary cutaneous extramedullary plasmacytoma secreting lambda IgG

Clin Exp Dermatol. 1993 Jul;18(4):351-5. doi: 10.1111/j.1365-2230.1993.tb02216.x.

Abstract

An adult male was described, who developed a tumour on his left arm, which was diagnosed as a primary cutaneous extramedullary plasmacytoma after histopathological, electron microscopic and immunocytochemical studies. Further studies ruled out the presence of multiple myeloma, extramedullary plasmacytoma of another site, or paraproteinaemia/paraproteinuria. During a relapse of the tumour 2 1/2 years after initial treatment, a new immunocytochemical study demonstrated that the tumour cells expressed monoclonal lambda IgG at the intracytoplasmic level, an unusual finding.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Humans
  • Immunoglobulin G / metabolism*
  • Male
  • Middle Aged
  • Plasmacytoma / immunology
  • Plasmacytoma / metabolism*
  • Skin Neoplasms / immunology
  • Skin Neoplasms / metabolism*

Substances

  • Immunoglobulin G