Trisomy 4 with double minute chromosomes in acute nonlymphocytic leukemia

Cancer Genet Cytogenet. 1993 Aug;69(1):41-4. doi: 10.1016/0165-4608(93)90111-x.

Abstract

We report on three further cases of trisomy 4 in acute nonlymphocytic leukemia. In one case the trisomy 4 was accompanied by double minute (dmin) chromosomes. Of the 34 reports of trisomy 4, dmin were also found in five cases, showing a clear nonrandom association between the two cytogenetic abnormalities.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bone Marrow Transplantation
  • Chromosome Aberrations*
  • Chromosomes, Human, Pair 4*
  • Combined Modality Therapy
  • Female
  • Humans
  • Leukemia, Myeloid, Acute / drug therapy
  • Leukemia, Myeloid, Acute / genetics*
  • Leukemia, Myeloid, Acute / surgery
  • Male
  • Middle Aged
  • Remission Induction
  • Trisomy*