Abstract
A 36 year old woman was admitted to our hospital for treatment of a high-grade rectal stenosis of unknown origin. She had a history of migraine going back 10 years. On intensive questioning she admitted using up to 5 ergotamine-containing suppositories a day. On the basis of history and clinical investigations the rectal stenosis must be connected with the abuse of ergotamine-containing suppositories. This case demonstrates that patients with an unexplained rectal syndrome should be asked for analgetics-containing suppositories specifically. Only discontinuation of treatment in time can preserve the patient from development of a rectal stenosis. In case of a rectal stenosis surgical treatment can be avoided by means of endoscopic controlled dilatation.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adult
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Aminopyrine / administration & dosage
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Aminopyrine / adverse effects*
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Biopsy
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Caffeine
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Colonoscopy
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Dilatation
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Drug Combinations
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Ergotamine / administration & dosage
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Ergotamine / adverse effects*
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Female
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Glycine / administration & dosage
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Glycine / adverse effects
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Glycine / analogs & derivatives*
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Humans
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Intestinal Obstruction / chemically induced*
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Intestinal Obstruction / pathology
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Intestinal Obstruction / therapy
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Ischemia / chemically induced
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Ischemia / pathology
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Migraine Disorders / drug therapy*
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Propylamines / administration & dosage
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Propylamines / adverse effects*
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Pyrazolones
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Rectal Diseases / chemically induced*
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Rectal Diseases / pathology
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Rectal Diseases / therapy
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Rectum / blood supply
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Suppositories
Substances
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Drug Combinations
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Propylamines
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Pyrazolones
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Suppositories
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caffeine, camylofin, ergotamine, mecloxamine, propyphenazone drug combination
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Aminopyrine
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Caffeine
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Ergotamine
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Glycine