Synthesis and characterization of human neutrophil elastase inhibitors derived from aromatic esters of phenylalkanoic acids

Agents Actions Suppl. 1993:42:71-82. doi: 10.1007/978-3-0348-7397-0_6.

Authors

G P Kirschenheuter¹, J Oleksyszyn, L W Spruce, M Wieczorek, T M Kloppel, S R Simon, J C Cheronis

Affiliation

¹ Cortech, Inc., Denver, CO 80221.

PMID: 8356932
DOI: 10.1007/978-3-0348-7397-0_6

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Endopeptidases / metabolism
Extracellular Matrix / enzymology
Humans
In Vitro Techniques
Kinetics
Leukocyte Elastase
Pancreatic Elastase / antagonists & inhibitors*
Phenylbutyrates / chemical synthesis
Phenylbutyrates / pharmacology*
Protease Inhibitors / pharmacology
Structure-Activity Relationship

Substances

Phenylbutyrates
Protease Inhibitors
Endopeptidases
Pancreatic Elastase
Leukocyte Elastase