Translocation (12;13) in a case of infantile fibrosarcoma

S Strehl; R Ladenstein; F Wrba; M Salzer-Kuntschik; H Gadner; P F Ambros

doi:10.1016/0165-4608(93)90207-3

Translocation (12;13) in a case of infantile fibrosarcoma

Cancer Genet Cytogenet. 1993 Nov;71(1):94-6. doi: 10.1016/0165-4608(93)90207-3.

Authors

S Strehl¹, R Ladenstein, F Wrba, M Salzer-Kuntschik, H Gadner, P F Ambros

Affiliation

¹ CCRI, Children's Cancer Research Institute, Vienna, Austria.

PMID: 8275459
DOI: 10.1016/0165-4608(93)90207-3

Abstract

Cytogenetic analysis of an infantile fibrosarcoma showed the presence of a t(12;13) and numerical changes of chromosomes 15 and 20. Until now only non-random gain or loss of total chromosomes as well as one case with a deletion at 17p have been reported for this kind of tumor. This report represents the first cytogenetic description of an aggressive infantile fibrosarcoma with a translocation.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Chromosomes, Human, Pair 12*
Chromosomes, Human, Pair 13*
Female
Fibrosarcoma / congenital*
Fibrosarcoma / genetics*
Humans
Infant
Thoracic Neoplasms / congenital
Thoracic Neoplasms / genetics
Translocation, Genetic*