The effect of acupuncture at Neiguan (P 6) on regulating hemorrhagic shock in 90 rabbits was observed. All the results suggested that acupuncture at Neiguan could raise blood pressure, protect cardiac pump function, correct the disturbance of secretion and metabolism of humoral factors, reduce blood adhesion to normal level and thus achieve anti-hemorrhagic shock. This study has provided scientific basis for expounding the mechanism of acupuncture in anti-shock.